New from eLife July 2, 2013
Now online at http://elife.elifesciences.org
Research Articles
The genome sequence of the colonial chordate, Botryllus schlosseri
Ayelet Voskoboynik, Norma F Neff, Debashis Sahoo, Aaron M Newman, Dmitry Pushkarev, Winston Koh, Benedetto Passarelli, H Christina Fan, Gary L Mantalas, Karla J Palmeri, Katherine J Ishizuka, Carmela Gissi, Francesca Griggio, Rachel Ben-Shlomo, Daniel M Corey, Lolita Penland, Richard A White, Irving L Weissman, Stephen R Quake
The first genome sequence of a colony-forming tunicate, Botryllus schlosseri, yields insights into the evolution of vertebrates, including the development of their immune system and vasculature.
Full text | PDF | eLife Digest
A longitudinal study of Caenorhabditis elegans larvae reveals a novel locomotion switch, regulated by Gαs signaling
Stanislav Nagy, Charles Wright, Nora Tramm, Nicholas Labello, Stanislav Burov, David Biron
C. elegans exhibits two distinct behavioral states, active and quiet wakefulness, and protein kinase A stabilizes active wakefulness through two of its major downstream targets.
Full text | PDF | eLife Digest
Fungal effector Ecp6 outcompetes host immune receptor for chitin binding through intrachain LysM dimerization
Andrea Sánchez-Vallet, Raspudin Saleem-Batcha, Anja Kombrink, Guido Hansen, Dirk-Jan Valkenburg, Bart PHJ Thomma, Jeroen R Mesters
Structural and biochemical analysis of a fungal LysM effector unveils a novel mechanism for chitin binding in which the concerted action of two LysM domains results in chitin binding with picomolar affinity.
Full text | PDF | eLife Digest
Fluorescent sensors reporting the activity of ammonium transceptors in live cells
Roberto De Michele, Cindy Ast, Dominique Loqué, Cheng-Hsun Ho, Susana LA Andrade, Viviane Lanquar, Guido Grossmann, Sören Gehne, Michael U Kumke, Wolf B Frommer
A modified form of Green Fluorescent Protein integrated into an ammonium transporter provides a sensor that can be used to monitor transport activity in vivo.
Full text | PDF | eLife Digest
See also: Insight by Yi Wang and Jonathan Javitch
Insight
Transport proteins: Getting to grips with ammonium
Yi Wang, Jonathan Javitch
Full text | PDF
Features
Making science count in government
Ian Boyd
Full text | PDF
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