Nature Reviews Neuroscience contents September 2013 Volume 14 Number 9 pp 587 - 664

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Autism: The Movement Perspective  Elizabeth B. Torres, Anne M. Donnellan and colleagues¦Frontiers in Integrative Neuroscience In this Research Topic the hosting editors bring movement to the forefront of autism research, diagnosis, and treatment. Researchers across disciplines have contributed to this Research Topic with the unifying goal of recognizing movement and sensory disturbances as core symptoms of the disorder.
TABLE OF CONTENTS
September 2013 Volume 14 Number 9
Impact Factor 31.673 *	In this issue Research Highlights Reviews Perspectives Also this month Article series: Neuroscience and the law  Featured article: The brain reward circuitry in mood disorders Scott J. Russo & Eric J. Nestler
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RESEARCH HIGHLIGHTS Top Techniques: Optogenetics takes more control p587 | doi:10.1038/nrn3580 Two new studies expand the optogenetic repertoire by showing light-induced inhibition of synaptic release and control of gene transcription and chromatin modifications. PDF Neuronal circuits: Staying connected during growth p588 | doi:10.1038/nrn3571 The location of glia is a key factor that determines synapse location during postembryonic growth in Caenorhabditis elegans. PDF Development: Branched for function p588 | doi:10.1038/nrn3579 The combined action of three transcription factors regulates mechanosensory neuron fate and branching in nematodes. PDF Glia: Transporting cargo from A to B p589 | doi:10.1038/nrn3568 Oligodendrocytes support neurons by releasing exosomes that are internalized by neurons, and the cargo that they contain is shown to provide metabolic support under conditions of cellular stress. PDF Motor control: A race to the (s)top p590 | doi:10.1038/nrn3569 Stopping a movement involves a race between distinct pathways through the basal ganglia that converge on the same neurons. PDF Sensory systems: Making a choice and sticking with it p590 | doi:10.1038/nrn3572 A new study reveals a signalling pathway that stabilizes the expression of a single olfactory receptor by an olfactory sensory neuron. PDF IN BRIEF Neurodegenerative disease: Lethal sequestration by mutant HTT | Neurological disorders: Counterproductive bias | Genetics: First step towards chromosome therapy | Addiction: Smoking and craving a drink? | Learning and memory: Falsifying memory | Motor systems: Practice drives efficiency | Learning and memory: Recognizing WNT signalling in memory | Neurotrophic factors: Deciphering fly neurotrophism PDF Neuroscience JOBS of the week Professor of Systems Neuroscience Professor of Neurogenetics ETH Tier 2 Canada Research Chair in Primate Neuroscience Western University Postdoctoral Scientist Columbia University Neurophysiology Postdoctoral Scholar The University of California Santa Barbara More Science jobs from Neuroscience EVENT Long-Term Potentiation: Enhancing Neuroscience for 40 Years 02.12.13 London, UK More science events from
REVIEWS		Top
Nuclear calcium signalling in the regulation of brain function Hilmar Bading p593 | doi:10.1038/nrn3531 Activity-dependent changes in neuronal gene expression require a means of synapse-to-nucleus signalling, and changes in nuclear calcium concentration provide a major route for such communication. Bading discusses how nuclear calcium signals are induced by synaptic activity and describes their role as regulators of gene expression in neuroadaptations. Abstract | Full Text | PDF
The brain reward circuitry in mood disorders Scott J. Russo & Eric J. Nestler p609 | doi:10.1038/nrn3381 Recent evidence suggests that mood disorders are associated with altered reward function. Russo and Nestler review studies that have shown alterations in the brain reward circuitry in patients with, and animal models of, depression, and discuss the cellular and molecular underpinnings of these alterations. Abstract | Full Text | PDF
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies David J. Irwin, Virginia M.-Y. Lee & John Q. Trojanowski p626 | doi:10.1038/nrn3549 Many cases of Parkinson's disease (PD) are characterized by not only deficits in movement but also cognitive dysfunction, which can develop into dementia. Here, Irwin et al. review the complex connections between the neuropathological aetiologies that underlie the cognitive deficits associated with PD. Abstract | Full Text | PDF
PERSPECTIVES		Top
OPINION Proteostasis in complex dendrites Cyril Hanus & Erin M. Schuman p638 | doi:10.1038/nrn3546 The implications of compartmentalization of protein synthesis and distribution within dendrites are not well understood. In this Opinion article, Hanus and Schuman discuss how the morphological complexity of dendrites and specialist regulatory mechanisms influence protein distribution and therefore the synaptic response to activity. Abstract | Full Text | PDF
SCIENCE AND SOCIETY Article series: Neuroscience and the law The neuroscience of memory: implications for the courtroom Joyce W. Lacy & Craig E. L. Stark p649 | doi:10.1038/nrn3563 Psychology and neuroscience studies have shown that memory is a reconstructive process that is susceptible to distortion. Lacy and Stark summarize the evidence and discuss how this insight could be applied to police and courtroom procedures. Abstract | Full Text | PDF
VIEWPOINT Neuroscience thinks big (and collaboratively) Eric R. Kandel, Henry Markram, Paul M. Matthews, Rafael Yuste & Christof Koch p659 | doi:10.1038/nrn3578 Nature Reviews Neuroscience asks five prominent neuroscientists about the goals of several ambitious collaborative projects that have attracted large amounts of funding and media attention in the past year. Abstract | Full Text | PDF
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Nature Reviews Neuroscience Article Series on Neuroscience and the law This Article Series explores the interaction between neuroscience and the legal system. Read discussions on issues pertaining to criminal responsibility, drug policy, memory and the dissemination of neuroscientific findings in the courtroom. Follow the series here: www.nature.com/nrn/series/neurosciencelaw
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*2012 Journal Citation Report (Thomson Reuters, 2013)

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