Nature Reviews Molecular Cell Biology contents September 2013 Volume 14 Number 9 pp543-606

Advertisement
The easiest NGS Library preparation you will ever find!  • Accurate library prep from picograms   • Simple 3-step protocol  • Perfect compatibility with ChIP samples down to 10,000 cells   • Automatable with the IP-Star Automation System  Learn more about Diagenode's MicroChIP and MicroPlex system.
TABLE OF CONTENTS
September 2013 Volume 14 Number 9		Advertisement
Impact Factor 37.162 *	In this issue Research Highlights Reviews Perspectives Also this month Article series: DNA damage Featured article: Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response H. Christian Reinhardt & Michael B. Yaffe	Just one of many high quality articles Frontiers in Microbiology has to offer:   Development of human dendritic cells and their role in HIV infection: antiviral immunity versus HIV transmission (open access) In this review, Yasuko Tsunetsugu-Yokota and Mahmod Muhsen summarize the current understanding about DC biology, antiviral immune responses and DC restriction factors, all of which will be important issues for the development of an effective AIDS vaccine in the future.
Subscribe   Facebook   RSS   Recommend to library   Twitter
Advertisement
nature.com webcasts Macmillan Science Communication presents a custom webcast on:  Personalized medicine: A framework for clinical genome sequencing in cancer  Listen on demand, to this free webcast  Sponsored by:
RESEARCH HIGHLIGHTS Top Development: Heads or tails p543 | doi:10.1038/nrm3650 The inability to regenerate heads from tail fragments in three planarian species can be reversed by downregulating WNT-β-catenin signalling. PDF Morphogenesis: Fuelling vessel sprouting p544 | doi:10.1038/nrm3649 PFKFB3-driven glycolysis promotes vessel sprouting during angiogenesis. PDF Non-coding RNAs: PIWI's new assistant p544 | doi:10.1038/nrm3656 GTSF1 is a key cofactor in Piwi-piRNA-mediated transposon silencing in Drosophila melanogaster. PDF Cell cycle: Getting to the centre p545 | doi:10.1038/nrm3648 Spindle positioning during anaphase depends on dynein and on asymmetric cell elongation. PDF Cell death: Balance through a bivalent regulator p546 | doi:10.1038/nrm3637 SPTF-3 promotes cell type-specific apoptosis through caspase-dependent and caspase-independent pathways. PDF Autophagy: Atg independence in the midgut p546 | doi:10.1038/nrm3646 Autophagy in the Drosophila melanogaster midgut is Atg7- and Atg3-independent. PDF STRUCTURE WATCH Unravelling class B GPCRs p546 | doi:10.1038/nrm3654 PDF STRUCTURE WATCH Brassinosteroid receptor activation p546 | doi:10.1038/nrm3655 PDF Membrane trafficking: Increasing Golgi transport options p548 | doi:10.1038/nrm3642 A role for EG5 in regulating post-Golgi transport during interphase. PDF JOURNAL CLUB V-SRC informs integrin signalling p548 | doi:10.1038/nrm3647 Experiments using SRC led to the discovery of focal adhesion kinase and the catenin p120ctn. PDF IN BRIEF Cell migration: How neutrophils set their compass | DNA damage: Facilitating repair | Technologies: Reducing the load of mtDNA mutations PDF Molecular Cell Biology JOBS of the week Postdoctoral Fellowships Baylor College of Medicine Postdoctoral Fellow Thomas Jefferson University Inner Ear Development and Regeneration Sunnybrook Research Institute Postdoctoral Position University Health Network (Toronto) Post Doctorate Researcher Istanbul University Institute of Experimental Medicine More Science jobs from Molecular Cell Biology EVENT Molecular Pathology and Diagnosis of Cancer 10.11.13 Cambridge, UK More science events from
REVIEWS		Top
Restarting life: fertilization and the transition from meiosis to mitosis Dean Clift & Melina Schuh p549 | doi:10.1038/nrm3643 Fertilization triggers a complex cellular programme that leads to a totipotent mitotic embryo. The molecular mechanisms underlying the meiosis to mitosis transition include changes in sister chromatid linkages, the reintroduction of a centrosome, a shift to symmetric cell division and changes in genomic imprinting and protein expression control. Abstract | Full Text | PDF
Article series: DNA damage Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response H. Christian Reinhardt & Michael B. Yaffe p563 | doi:10.1038/nrm3640 Phospho-Ser/Thr-binding domains are crucial regulators of cell cycle progression and DNA damage signalling. Progress has been made in our understanding of the motif (or motifs) that these domains connect with on their target proteins and precisely how these interactions influence the cell cycle and DNA damage response. Abstract | Full Text | PDF | Supplementary information
Mechanisms and mechanics of cell competition in epithelia Jean-Paul Vincent, Alexander G. Fletcher & L. ALberto Baena-Lopez p581 | doi:10.1038/nrm3639 Cell competition occurs when cells that grow at different rates confront each other. This results in the elimination of the slower growing cells by apoptosis. Although exactly how this occurs is unclear, mechanical factors might be involved, as cell crowding within an epithelium leads to delamination and extrusion. Abstract | Full Text | PDF
PERSPECTIVES		Top
OPINION Protein adaptation: mitotic functions for membrane trafficking proteins Stephen J. Royle p592 | doi:10.1038/nrm3641 A growing list of membrane trafficking regulators, particularly those affecting clathrin-mediated endocytosis, have independent functions in mitosis. This repurposing may have arisen from the functional flexibility of the membrane trafficking machinery. Abstract | Full Text | PDF
ESSAY In focus: molecular and cell biology research in China Xuebiao Yao, Dangsheng Li & Gang Pei p600 | doi:10.1038/nrm3638 The fast-growing economy and investment in science, including new funding opportunities and career development initiatives, have attracted foreign scholars to work in China and motivated world-class Chinese scientists to return. As a result, molecular and cell biology research in China has evolved rapidly over the past decade. Abstract | Full Text | PDF
Advertisement
CNIO, Nature, Nature Cell Biology and Nature Reviews Cancer present: CNIO Cancer Symposium: Frontiers in Tumor Heterogeneity and Plasticity October 27-30, 2013 Madrid, Spain  Click here for more information or to register for this conference today!
Natureevents is a fully searchable, multi-disciplinary database designed to maximise exposure for events organisers. The contents of the Natureevents Directory are now live. The digital version is available here. Find the latest scientific conferences, courses, meetings and symposia on natureevents.com. For event advertising opportunities across the Nature Publishing Group portfolio please contact natureevents@nature.com More Nature Events

*2011 Journal Citation Report (Thomson Reuters, 2012)

You have been sent this Table of Contents Alert because you have opted in to receive it. You can change or discontinue your e-mail alerts at any time, by modifying your preferences on your nature.com account at: www.nature.com/myaccount (You will need to log in to be recognised as a nature.com registrant). For further technical assistance, please contact our registration department For print subscription enquiries, please contact our subscription department For other enquiries, please contact our feedback department Nature Publishing Group | 75 Varick Street, 9th Floor | New York | NY 10013-1917 | USA Nature Publishing Group's worldwide offices: London - Paris - Munich - New Delhi - Tokyo - Melbourne San Diego - San Francisco - Washington - New York - Boston Macmillan Publishers Limited is a company incorporated in England and Wales under company number 785998 and whose registered office is located at Brunel Road, Houndmills, Basingstoke, Hampshire RG21 6XS. © 2013 Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.