Scientific Reports Health Sciences Table of Contents e-alert: July 2013

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	CORRIGENDUM: A novel human endogenous retroviral protein inhibits cell-cell fusion ▶     Jun Sugimoto, Makiko Sugimoto, Helene Bernstein et al.                 Impaired automatic and unconscious motor processes in Parkinson's disease ▶     Kevin D'Ostilio, Julien Cremers, Valérie Delvaux et al.     While it is increasingly recognized that voluntary movements are produced by an interaction between conscious and unconscious processes, the role of the latter in Parkinson's …             Concentration polarization of ox-LDL activates autophagy and apoptosis via regulating LOX-1expression ▶     Zufeng Ding, Shijie Liu, Changqing Sun et al.     Here we demonstrate that “concentration polarization” of ox-LDL enhances LOX-1 expression and ox-LDL uptake. It damages cell surface heparan sulfate proteoglycans (HSPG) and …             Application of “Papillary-Like Main Pancreatic Duct Invaginated” Pancreaticojejunostomy for Normal Soft Pancreas Cases ▶     Bo Zhang, Jin Xu, Chen Liu et al.     Pancreaticojejunostomy is the key procedure of pancreaticoduodenectomy. Our study introduced a new pancreaticojejunal (PJ) anastomosis named “papillary-like main pancreatic duct …             Metformin Impairs Glucose Consumption and Survival in Calu-1 Cells by Direct Inhibition of Hexokinase-II ▶     Barbara Salani, Cecilia Marini, Alberto Del Rio et al.     The anti-hyperglycaemic drug metformin has important anticancer properties as shown by the direct inhibition of cancer cells proliferation. Tumor cells avidly use glucose as a …             In vitro circadian period is associated with circadian/sleep preference ▶     Akiko Hida, Shingo Kitamura, Yosuke Ohsawa et al.     Evaluation of circadian phenotypes is crucial for understanding the pathophysiology of diseases associated with disturbed biological rhythms such as circadian rhythm sleep …             A novel method for semen collection and artificial insemination in large parrots (Psittaciformes) ▶     Michael Lierz, Matthias Reinschmidt, Heiner Müller et al.     The paper described a novel technique for semen collection in large psittacines (patent pending), a procedure which was not routinely possible before. For the first time, a large …             Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men ▶     Emma Killick, Richard Morgan, Francesca Launchbury et al.     Controversy surrounds the use of PSA as a biomarker for prostate cancer detection, leaving an unmet need for a novel biomarker in this setting; urinary EN2 may identify …             VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival ▶     Piotr Religa, Renhai Cao, Dorota Religa et al.     The functional impact of amyloid peptides (Aβs) on the vascular system is less understood despite these pathologic peptides are substantially deposited in the brain vasculature of …             A Quantitative Meta-Analysis of Functional Imaging Studies of Social Rejection ▶     Stephanie Cacioppo, Chris Frum, Erik Asp et al.     Early neuroimaging studies using Cyberball suggested that social rejection activated the pain matrix, as identified in studies of physical pain. However, these early studies were …             Unraveling dynamics of human physical activity patterns in chronic pain conditions ▶     Anisoara Paraschiv-Ionescu, Eric Buchser, Kamiar Aminian     Chronic pain is a complex disabling experience that negatively affects the cognitive, affective and physical functions as well as behavior. Although the interaction between …             The fatigue-motor performance paradox in multiple sclerosis ▶     Matteo Pardini, Laura Bonzano, Luca Roccatagliata et al.     Subjective fatigue is a typical symptom in Multiple Sclerosis (MS) even in the earliest stages of the disease. The relationship between persistent fatigue and motor task …             Common dysfunctional variants in ABCG2 are a major cause of early-onset gout ▶     Hirotaka Matsuo, Kimiyoshi Ichida, Tappei Takada et al.     Gout is a common disease which mostly occurs after middle age, but more people nowadays develop it before the age of thirty. We investigated whether common dysfunction of ABCG2, a …             A TRPA1 antagonist reverts oxaliplatin-induced neuropathic pain ▶     Cristina Nativi, Roberta Gualdani, Elisa Dragoni et al.     Neuropathic pain (NeP) is generally considered an intractable problem, which becomes compelling in clinical practice when caused by highly effective chemotherapeutics, such as in …             Comparative population structure of Plasmodium falciparum circumsporozoite protein NANP repeat lengths in Lilongwe, Malawi ▶     Natalie M. Bowman, Seth Congdon, Tisungane Mvalo et al.     Humoral immunity to Plasmodium falciparum circumsporozoite protein is partly mediated by a polymorphic NANP tetra-amino acid repeat. Antibody response to these repeats is the best …             Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria ▶     Noriyuki Nagahara, Masatoshi Nagano, Takaaki Ito et al.     Human mercaptolactate-cysteine disulfiduria (MCDU) was first recognized and reported in 1968. Most cases of MCD are associated with mental retardation, while the pathogenesis …             Morphine induced exacerbation of sepsis is mediated by tempering endotoxin tolerance through modulation of miR-146a ▶     Santanu Banerjee, Jingjing Meng, Subhas Das et al.     Development of tolerance to endotoxin prevents sustained hyper inflammation during systemic infections. Here we report for the first time that chronic morphine treatment tempers …             Mahogunin ring finger-1 (MGRN1) Suppresses Chaperone-Associated Misfolded Protein Aggregation and Toxicity ▶     Deepak Chhangani, Amit Mishra     Impairment in the elimination of misfolded proteins generates cellular toxicity and leads to various late-onset neurodegenerative diseases. However, the mechanisms by which cells …             Effects of genetically modified T2A-1 rice on the GI health of rats after 90-day supplement ▶     Yanfang Yuan, Wentao Xu, Xiaoyun He et al.     Bacillus thuringiensis insecticidal toxin (Bt) rice will be commercialized as a main food source. Traditional safety assessments on genetically modified products pay little …             Placenta-derived gp96 as a multivalent prophylactic cancer vaccine ▶     Bao Zhao, Yanzhong Wang, Bo Wu et al.     A major challenge for designing prophylactic cancer vaccines is to define immunogenic and safe cancer antigens. Given the striking similarity of antigen expression patterns …             Novel n-3 Immunoresolvents: Structures and Actions ▶     Jesmond Dalli, Romain A. Colas, Charles N. Serhan     Resolution of inflammation is now held to be an active process where autacoids promote homeostasis. Using functional-metabololipidomics and in vivo systems, herein we report that …
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