Tuesday 17 September 2013

New articles from eLife - September 17, 2013

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New from eLife September 17, 2013
Now online at http://elife.elifesciences.org

Research Articles

Caveolae internalization repairs wounded cells and muscle fibers
Matthias Corrotte, Patricia E Almeida, Christina Tam, Thiago Castro-Gomes, Maria Cecilia Fernandes, Bryan A Millis, Mauro Cortez, Heather Miller, Wenxia Song, Timothy K Maugel, Norma Andrews

Cells repair damage to their outer membranes not by patching them as previously thought, but by using proteins called caveolins to remove the damaged regions by endocytosis.
Full text | PDF | eLife Digest

The structure of the COPII transport-vesicle coat assembled on membranes
Giulia Zanetti, Simone Prinz, Sebastian Daum, Annette Meister, Randy Schekman, Kirsten Bacia, John AG Briggs

A structure of the complete, membrane bound, COPII coat solved by sub-tomogram averaging reveals the arrangement of all protein subunits on the membrane and suggests a mechanism for coating heterogeneously-shaped carriers.
Full text | PDF | eLife Digest

Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly
Matthew A Cottee, Nadine Muschalik, Yao Liang Wong, Christopher M Johnson, Steven Johnson, Antonina Andreeva, Karen Oegema, Susan M Lea, Jordan W Raff, Mark van Breugel

Crystal structures of the CPAP-STIL centriole duplication complex provide a structural explanation for a human microcephaly mutation.
Full text | PDF | eLife Digest

The antigenic switching network of Plasmodium falciparum and its implications for the immuno-epidemiology of malaria
Robert Noble, Zóe Christodoulou, Sue Kyes, Robert Pinches, Chris I Newbold, Mario Recker

The first comprehensive analysis of antigenic switching in the malaria-causing parasite Plasmodium falciparum provides new insights into the process that prevents individuals from acquiring immunity to the disease.
Full text | PDF | eLife Digest

MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons
Caitlin Engelhard, Sarah Sarsfield, Janna Merte, Qiang Wang, Peng Li, Hideyuki Beppu, Alex L Kolodkin, Henry M Sucov, David D Ginty

A protein called Megf8 regulates the activity of key signaling molecules involved in the development of the peripheral nervous system.
Full text | PDF | eLife Digest

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