Scientific Reports Table of Contents e-alert: 13 August 2013

13 August 2013      • Visit Scientific Reports • Submit your manuscript to Scientific Reports     Welcome to your Table of Contents e-alert for Scientific Reports             Jump to the content that matters to you ▼ Biological Sciences   ▼ Chemical Sciences   ▼ Physical Sciences   ▼ Earth & Environmental Sciences   ▼ Health Sciences               Biological Sciences ▲ top               Single nucleotide polymorphisms in the mitochondrial displacement loop and age-at onset of renal cell carcinoma ▶     Jinsheng Xu, Zhanjun Guo, Junxia Zhang et al.     The accumulation of single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) has been described in various types of cancers, and their …             X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk ▶     Rut Fadó, Rana S. Moubarak, Alfredo J. Miñano-Molina et al.     X-linked Inhibitor of apoptosis protein (XIAP) has been classically identified as a cell death regulator. Here, we demonstrate a novel function of XIAP as a regulator of neurite …             Growth in rice cells requires de novo purine biosynthesis by the blast fungus Magnaporthe oryzae ▶     Jessie Fernandez, Kuan Ting Yang, Kathryn M. Cornwell et al.     Increasing incidences of human disease, crop destruction and ecosystem perturbations are attributable to fungi and threaten socioeconomic progress and food security on a global …             Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation ▶     Munerah Hamed, Saadia Khilji, Jihong Chen et al.     While chromatin modifications can offer a useful readout for enhancer activities, it is less clear whether these modification marks are a cause or consequence of transcription …             Humanlike robot hands controlled by brain activity arouse illusion of ownership in operators ▶     Maryam Alimardani, Shuichi Nishio, Hiroshi Ishiguro     Operators of a pair of robotic hands report ownership for those hands when they hold image of a grasp motion and watch the robot perform it. We present a novel body ownership …             Association of telomere shortening in myocardium with heart weight gain and cause of death ▶     Masanori Terai, Naotaka Izumiyama-Shimomura, Junko Aida et al.     We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly …             The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis ▶     Arasukumar Subramani, Samer Alsidawi, Sajjeev Jagannathan et al.     The brain microenvironment promotes metastasis through mechanisms that remain elusive. Co-culture of lung cancer cells with astrocytes - the most abundant cell type within the …             Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation ▶     Makoto Fujii, Katsuhisa Kawai, Youhei Egami et al.     Macropinocytosis, a fluid-phase endocytosis, is a crucial pathway for antigen uptake and presentation in macrophages. We attempted to characterise the activation and deactivation …             Arginine insertion and loss of N-linked glycosylation site in HIV-1 envelope V3 region confer CXCR4-tropism ▶     Kiyoto Tsuchiya, Hirotaka Ode, Tsunefusa Hayashida et al.     The third variable region (V3) of HIV-1 envelope glycoprotein gp120 plays a key role in determination of viral coreceptor usage (tropism). However, which combinations of mutations …             The Directive 2010/63/EU on animal experimentation may skew the conclusions of pharmacological and behavioural studies ▶     Simone Macrì, Chiara Ceci, Luisa Altabella et al.     All laboratory animals shall be provided some form of environmental enrichment (EE) in the nearest future (Directive 2010/63/EU). Displacing standard housing with EE entails the …             Aetiologies of Central Nervous System infections in adults in Kathmandu, Nepal: A prospective hospital-based study ▶     Abhishek Giri, Amit Arjyal, Samir Koirala et al.     We conducted a prospective hospital based study from February 2009-April 2011 to identify the possible pathogens of central nervous system (CNS) infections in adults admitted to a …             FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD ▶     Yusuke Fujioka, Shinsuke Ishigaki, Akio Masuda et al.     FUS is genetically and pathologically linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). To clarify the RNA metabolism cascade regulated …             Identification and super-resolution imaging of ligand-activated receptor dimers in live cells ▶     Pascale Winckler, Lydia Lartigue, Gregory Giannone et al.     Molecular interactions are key to many chemical and biological processes like protein function. In many signaling processes they occur in sub-cellular areas displaying nanoscale …             Mannosylglucosylglycerate biosynthesis in the deep-branching phylum Planctomycetes: characterization of the uncommon enzymes from Rhodopirellula baltica ▶     Sofia Cunha, Ana Filipa d'Avó, Ana Mingote et al.     The biosynthetic pathway for the rare compatible solute mannosylglucosylglycerate (MGG) accumulated by Rhodopirellula baltica, a marine member of the phylum Planctomycetes, has …             Induction of antiviral genes by the tumor microenvironment confers resistance to virotherapy ▶     Yu-Ping Liu, Lukkana Suksanpaisan, Michael B. Steele et al.     Oncolytic viruses obliterate tumor cells in tissue culture but not against the same tumors in vivo. We report that macrophages can induce a powerfully protective antiviral state …             Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing ▶     Wei Yan, Cory Smith, Linzhao Cheng     Our ability to precisely and efficiently edit mammalian and plant genomes has been significantly improved in recent years, partially due to increasing use of designer nucleases …             System-dependent regulations of colour-pattern development: a mutagenesis study of the pale grass blue butterfly ▶     Masaki Iwata, Atsuki Hiyama, Joji M. Otaki     Developmental studies on wing colour patterns have been performed in nymphalid butterflies, but efficient genetic manipulations, including mutagenesis, have not been well …             CORRIGENDUM: The biological impacts of the Fukushima nuclear accident on the pale grass blue butterfly ▶     Atsuki Hiyama, Chiyo Nohara, Seira Kinjo et al.                 Ptychography – a label free, high-contrast imaging technique for live cells using quantitative phase information ▶     Joanne Marrison, Lotta Räty, Poppy Marriott et al.     Cell imaging often relies on synthetic or genetic fluorescent labels, to provide contrast which can be far from ideal for imaging cells in their in vivo state. We report on the …             A ground-like surface facilitates visual search in chimpanzees (Pan troglodytes) ▶     Tomoko Imura, Masaki Tomonaga     Ground surfaces play an important role in terrestrial species' locomotion and ability to manipulate objects. In humans, ground surfaces have been found to offer significant …             Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? ▶     Lyubov V. Titova, Ayesheshim K. Ayesheshim, Andrey Golubov et al.     Terahertz (THz) radiation lies between the infrared and microwave regions of the electromagnetic spectrum and is non-ionizing. We show that exposure of artificial human skin …             STAT6 promotes bi-directional modulation of PKM2 in liver and adipose inflammatory cells in Rosiglitazone-treated mice ▶     Tatjana Sajic, Alexandre Hainard, Alexander Scherl et al.     STAT6 interacts with PPARγ to elicit macrophage polarization towards an anti-inflammatory, insulin-sensitizing phenotype. Mice deficient in STAT6 display liver lipid accumulation …             Metabolic profiling of Alzheimer's disease brains ▶     Koichi Inoue, Haruhito Tsutsui, Hiroyasu Akatsu et al.     Alzheimer's disease (AD) is an irreversible, progressive brain disease and can be definitively diagnosed after death through an examination of senile plaques and neurofibrillary …             Bioactive baculovirus nanohybrids for stent based rapid vascular re-endothelialization ▶     Arghya Paul, Cynthia B. Elias, Dominique Shum-Tim et al.     Present study, for the first time, reports the development of a nanohybridized baculovirus based stent that can locally promote vascular re-endothelialization by efficient …                 LEARNING IN THE DIGITAL AGE Nature and Scientific American collaborate to probe the revolution underway in education and discuss what it means for learning, teaching and research.   Access the Special online or via specials in the NatureJournals app          Chemical Sciences ▲ top               Submerged Liquid Plasma for the Synthesis of Unconventional Nitrogen Polymers ▶     Jaganathan Senthilnathan, Chih-Chiang Weng, Jiunn-Der Liao et al.     Glow discharge polymerization is not well understood due to the rapid/complex reaction at the plasma/gas precursor interface. Plasma reaction in a submerged condition allows …             Improvement of Thiolate/Disulfide Mediated Dye-Sensitized Solar Cells through Supramolecular Lithium Cation Assembling of Crown Ether ▶     Linfeng Liu, Xiong Li, Jiangzhao Chen et al.     A supramolecular lithium cation assemblies of crown ether, [Li⊂12-crown-4], has been used to replace conventional tetraalkylammonium counterion in thiolate/disulfide (ET−/BET) …             Friction coefficient dependence on electrostatic tribocharging ▶     Thiago A. L. Burgo, Cristiane A. Silva, Lia B. S. Balestrin et al.     Friction between dielectric surfaces produces patterns of fixed, stable electric charges that in turn contribute electrostatic components to surface interactions between the …             A full-sunlight-driven photocatalyst with super long-persistent energy storage ability ▶     Jie Li, Yuan Liu, Zhijian Zhu et al.     A major drawback of traditional photocatalysts like TiO2 is that they can only work under illumination, and the light has to be UV. As a solution for this limitation, …             A Comprehensive Strategy to Boost the Quantum Yield of Luminescence of Europium Complexes ▶     Nathalia B. D. Lima, Simone M. C. Gonçalves, Severino A. Júnior et al.     Lanthanide luminescence has many important applications in anion sensing, protein recognition, nanosized phosphorescent devices, optoelectronic devices, immunoassays, etc. …             Noise induced oscillations and coherence resonance in a generic model of the nonisothermal chemical oscillator ▶     David S. A. Simakov, Juan Pérez-Mercader     Oscillating chemical reactions are common in biological systems and they also occur in artificial non-biological systems. Generally, these reactions are subject to random …             Atomic Structures of Silicene Layers Grown on Ag(111): Scanning Tunneling Microscopy and Noncontact Atomic Force Microscopy Observations ▶     Andrea Resta, Thomas Leoni, Clemens Barth et al.     Silicene, the considered equivalent of graphene for silicon, has been recently synthesized on Ag(111) surfaces. Following the tremendous success of graphene, silicene might …             Multiscale distribution of oxygen puddles in 1/8 doped YBa2Cu3O6.67 ▶     Alessandro Ricci, Nicola Poccia, Gaetano Campi et al.     Despite intensive research a physical explanation of high Tc superconductors remains elusive. One reason for this is that these materials have generally a very complex structure …             "Re-growth Etching" to Large-sized Porous Gold Nanostructures ▶     Wenzheng Li, Long Kuai, Lu Chen et al.     A new method, named "re-growth etching", which introduces a unique etchant "AuI", has been developed to fabricate large-sized porous gold nanostructures. The size of …             Rapid (<5 min) Identification of Pathogen in Human Blood by Electrokinetic Concentration and Surface-Enhanced Raman Spectroscopy ▶     I-Fang Cheng, Hsien-Chang Chang, Tzu-Ying Chen et al.     This study reports a novel microfluidic platform for rapid and long-ranged concentration of rare-pathogen from human blood for subsequent on-chip surface-enhanced Raman …             A supramolecular approach to fabricate highly emissive smart materials ▶     Kai Liu, Yuxing Yao, Yuetong Kang et al.     The aromatic chromophores, for example, perylene diimides (PDIs) are well known for their desirable absorption and emission properties. However, their stacking nature hinders the …             Structurally Coloured Secondary Particles Composed of Black and White Colloidal Particles ▶     Yukikazu Takeoka, Shinya Yoshioka, Midori Teshima et al.     This study investigated the colourful secondary particles formed by controlling the aggregation states of colloidal silica particles and the enhancement of the structural …             Liquid crystal self-templating approach to ultrastrong and tough biomimic composites ▶     Xiaozhen Hu, Zhen Xu, Zheng Liu et al.     Materials with both high strength and toughness are in great demand for a wide range of applications, requiring strict design of ingredients and hierarchically ordered …             Quantum Transport Enhancement by Time-Reversal Symmetry Breaking ▶     Zoltán Zimborás, Mauro Faccin, Zoltán Kádár et al.     Quantum mechanics still provides new unexpected effects when considering the transport of energy and information. Models of continuous time quantum walks, which implicitly use …             Metabolic profiling of Alzheimer's disease brains ▶     Koichi Inoue, Haruhito Tsutsui, Hiroyasu Akatsu et al.     Alzheimer's disease (AD) is an irreversible, progressive brain disease and can be definitively diagnosed after death through an examination of senile plaques and neurofibrillary …                     Physical Sciences ▲ top               ERRATUM: Nanocontainers made of Various Materials with Tunable Shape and Size ▶     Xianglong Zhao, Guowen Meng, Fangming Han et al.                 Improvement of Thiolate/Disulfide Mediated Dye-Sensitized Solar Cells through Supramolecular Lithium Cation Assembling of Crown Ether ▶     Linfeng Liu, Xiong Li, Jiangzhao Chen et al.     A supramolecular lithium cation assemblies of crown ether, [Li⊂12-crown-4], has been used to replace conventional tetraalkylammonium counterion in thiolate/disulfide (ET−/BET) …             Submerged Liquid Plasma for the Synthesis of Unconventional Nitrogen Polymers ▶     Jaganathan Senthilnathan, Chih-Chiang Weng, Jiunn-Der Liao et al.     Glow discharge polymerization is not well understood due to the rapid/complex reaction at the plasma/gas precursor interface. Plasma reaction in a submerged condition allows …             Improvement of infrared single-photon detectors absorptance by integrated plasmonic structures ▶     Mária Csete, Áron Sipos, Anikó Szalai et al.     Plasmonic structures open novel avenues in photodetector development. Optimized illumination configurations are reported to improve p-polarized light absorptance in …             The antiferromagnetic structures of IrMn3 and their influence on exchange-bias ▶     A. Kohn, A. Kovács, R. Fan et al.     We have determined the magnetic structures of single-crystal thin-films of IrMn3 for the crystallographic phases of chemically-ordered L12, and for chemically-disordered …             Strong Temporal Variation Over One Saturnian Year: From Voyager to Cassini ▶     Liming Li, Richard K. Achterberg, Barney J. Conrath et al.     Here we report the combined spacecraft observations of Saturn acquired over one Saturnian year (~29.5 Earth years), from the Voyager encounters (1980–81) to the new Cassini …             Tunable Dirac Fermion Dynamics in Topological Insulators ▶     Chaoyu Chen, Zhuojin Xie, Ya Feng et al.     Three-dimensional topological insulators are characterized by insulating bulk state and metallic surface state involving relativistic Dirac fermions which are responsible for …             Multimode Resistive Switching in Single ZnO Nanoisland System ▶     Jing Qi, Mario Olmedo, Jian-Guo Zheng et al.     Resistive memory has attracted a great deal of attention as an alternative to contemporary flash memory. Here we demonstrate an interesting phenomenon that multimode resistive …             Friction coefficient dependence on electrostatic tribocharging ▶     Thiago A. L. Burgo, Cristiane A. Silva, Lia B. S. Balestrin et al.     Friction between dielectric surfaces produces patterns of fixed, stable electric charges that in turn contribute electrostatic components to surface interactions between the …             A full-sunlight-driven photocatalyst with super long-persistent energy storage ability ▶     Jie Li, Yuan Liu, Zhijian Zhu et al.     A major drawback of traditional photocatalysts like TiO2 is that they can only work under illumination, and the light has to be UV. As a solution for this limitation, …             A Comprehensive Strategy to Boost the Quantum Yield of Luminescence of Europium Complexes ▶     Nathalia B. D. Lima, Simone M. C. Gonçalves, Severino A. Júnior et al.     Lanthanide luminescence has many important applications in anion sensing, protein recognition, nanosized phosphorescent devices, optoelectronic devices, immunoassays, etc. …             Tuning universality far from equilibrium ▶     Markus Karl, Boris Nowak, Thomas Gasenzer     Possible universal dynamics of a many-body system far from thermal equilibrium are explored. A focus is set on meta-stable non-thermal states exhibiting critical properties such …             Noise induced oscillations and coherence resonance in a generic model of the nonisothermal chemical oscillator ▶     David S. A. Simakov, Juan Pérez-Mercader     Oscillating chemical reactions are common in biological systems and they also occur in artificial non-biological systems. Generally, these reactions are subject to random …             Atomic Structures of Silicene Layers Grown on Ag(111): Scanning Tunneling Microscopy and Noncontact Atomic Force Microscopy Observations ▶     Andrea Resta, Thomas Leoni, Clemens Barth et al.     Silicene, the considered equivalent of graphene for silicon, has been recently synthesized on Ag(111) surfaces. Following the tremendous success of graphene, silicene might …             Quantum Corrections Crossover and Ferromagnetism in Magnetic Topological Insulators ▶     Lihong Bao, Weiyi Wang, Nicholas Meyer et al.     Revelation of emerging exotic states of topological insulators (TIs) for future quantum computing applications relies on breaking time-reversal symmetry and opening a surface …             One-step spray processing of high power all-solid-state supercapacitors ▶     Chun Huang, Patrick S. Grant     Aqueous suspensions of multi-wall carbon nanotubes (MWNTs) in dilute H2SO4 were sprayed onto both sides of a Nafion membrane and dried to fabricate flexible solid-state …             Detecting orbital angular momentum through division-of-amplitude interference with a circular plasmonic lens ▶     Ai-Ping Liu, Xiao Xiong, Xi-Feng Ren et al.     We demonstrate a novel detection scheme for the orbital angular momentum (OAM) of light using circular plasmonic lens. Owing to a division-of-amplitude interference phenomenon …             Decision Maker based on Nanoscale Photo-excitation Transfer ▶     Song-Ju Kim, Makoto Naruse, Masashi Aono et al.     Decision-making is one of the most important intellectual abilities of the human brain. Here we propose an efficient decision-making system which uses optical energy transfer …             Effect of mass disorder on the lattice thermal conductivity of MgO periclase under pressure ▶     Douglas Allen Dalton, Wen-Pin Hsieh, Gregory T. Hohensee et al.     Thermal conductivity of mantle materials controlling the heat balance and thermal evolution of the Earth remains poorly constrained as the available experimental and theoretical …             Humanlike robot hands controlled by brain activity arouse illusion of ownership in operators ▶     Maryam Alimardani, Shuichi Nishio, Hiroshi Ishiguro     Operators of a pair of robotic hands report ownership for those hands when they hold image of a grasp motion and watch the robot perform it. We present a novel body ownership …             Multiscale distribution of oxygen puddles in 1/8 doped YBa2Cu3O6.67 ▶     Alessandro Ricci, Nicola Poccia, Gaetano Campi et al.     Despite intensive research a physical explanation of high Tc superconductors remains elusive. One reason for this is that these materials have generally a very complex structure …             Identification and super-resolution imaging of ligand-activated receptor dimers in live cells ▶     Pascale Winckler, Lydia Lartigue, Gregory Giannone et al.     Molecular interactions are key to many chemical and biological processes like protein function. In many signaling processes they occur in sub-cellular areas displaying nanoscale …             "Re-growth Etching" to Large-sized Porous Gold Nanostructures ▶     Wenzheng Li, Long Kuai, Lu Chen et al.     A new method, named "re-growth etching", which introduces a unique etchant "AuI", has been developed to fabricate large-sized porous gold nanostructures. The size of …             A self-assembled three-dimensional cloak in the visible ▶     Stefan Mühlig, Alastair Cunningham, José Dintinger et al.     An invisibility cloak has been designed, realized and characterized. The cloak hides free-standing sub-wavelength three-dimensional objects at the short wavelength edge of the …             Structurally Coloured Secondary Particles Composed of Black and White Colloidal Particles ▶     Yukikazu Takeoka, Shinya Yoshioka, Midori Teshima et al.     This study investigated the colourful secondary particles formed by controlling the aggregation states of colloidal silica particles and the enhancement of the structural …             Rapid (<5 min) Identification of Pathogen in Human Blood by Electrokinetic Concentration and Surface-Enhanced Raman Spectroscopy ▶     I-Fang Cheng, Hsien-Chang Chang, Tzu-Ying Chen et al.     This study reports a novel microfluidic platform for rapid and long-ranged concentration of rare-pathogen from human blood for subsequent on-chip surface-enhanced Raman …             Liquid crystal self-templating approach to ultrastrong and tough biomimic composites ▶     Xiaozhen Hu, Zhen Xu, Zheng Liu et al.     Materials with both high strength and toughness are in great demand for a wide range of applications, requiring strict design of ingredients and hierarchically ordered …             Quantum Transport Enhancement by Time-Reversal Symmetry Breaking ▶     Zoltán Zimborás, Mauro Faccin, Zoltán Kádár et al.     Quantum mechanics still provides new unexpected effects when considering the transport of energy and information. Models of continuous time quantum walks, which implicitly use …             Biodegradability engineering of biodegradable Mg alloys: Tailoring the electrochemical properties and microstructure of constituent phases ▶     Pil-Ryung Cha, Hyung-Seop Han, Gui-Fu Yang et al.     Crystalline Mg-based alloys with a distinct reduction in hydrogen evolution were prepared through both electrochemical and microstructural engineering of the constituent phases. …             Fabrication of ultra-thin nanostructured bimetallic foils by Accumulative Roll Bonding and Asymmetric Rolling ▶     Hailiang Yu, Cheng Lu, A. Kiet Tieu et al.     This paper reports a new technique that combines the features of Accumulative Roll Bonding (ARB) and Asymmetric Rolling (AR). This technique has been developed to enable …             Arbitrary Multicolor Photodetection by Hetero-integrated Semiconductor Nanostructures ▶     Liwen Sang, Junqing Hu, Rujia Zou et al.     The typical photodetectors can only detect one specific optical spectral band, such as InGaAs and graphene-PbS quantum dots for near-infrared (NIR) light detection, CdS and Si for …             Bioactive baculovirus nanohybrids for stent based rapid vascular re-endothelialization ▶     Arghya Paul, Cynthia B. Elias, Dominique Shum-Tim et al.     Present study, for the first time, reports the development of a nanohybridized baculovirus based stent that can locally promote vascular re-endothelialization by efficient …             A supramolecular approach to fabricate highly emissive smart materials ▶     Kai Liu, Yuxing Yao, Yuetong Kang et al.     The aromatic chromophores, for example, perylene diimides (PDIs) are well known for their desirable absorption and emission properties. However, their stacking nature hinders the …             Metabolic profiling of Alzheimer's disease brains ▶     Koichi Inoue, Haruhito Tsutsui, Hiroyasu Akatsu et al.     Alzheimer's disease (AD) is an irreversible, progressive brain disease and can be definitively diagnosed after death through an examination of senile plaques and neurofibrillary …               Earth & Environmental Sciences ▲ top               A full-sunlight-driven photocatalyst with super long-persistent energy storage ability ▶     Jie Li, Yuan Liu, Zhijian Zhu et al.     A major drawback of traditional photocatalysts like TiO2 is that they can only work under illumination, and the light has to be UV. As a solution for this limitation, …             Effect of mass disorder on the lattice thermal conductivity of MgO periclase under pressure ▶     Douglas Allen Dalton, Wen-Pin Hsieh, Gregory T. Hohensee et al.     Thermal conductivity of mantle materials controlling the heat balance and thermal evolution of the Earth remains poorly constrained as the available experimental and theoretical …             CORRIGENDUM: The biological impacts of the Fukushima nuclear accident on the pale grass blue butterfly ▶     Atsuki Hiyama, Chiyo Nohara, Seira Kinjo et al.                   Health Sciences ▲ top               The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis ▶     Arasukumar Subramani, Samer Alsidawi, Sajjeev Jagannathan et al.     The brain microenvironment promotes metastasis through mechanisms that remain elusive. Co-culture of lung cancer cells with astrocytes - the most abundant cell type within the …             Association of telomere shortening in myocardium with heart weight gain and cause of death ▶     Masanori Terai, Naotaka Izumiyama-Shimomura, Junko Aida et al.     We attempted to clarify myocardial telomere dynamics using samples from 530 autopsied patients using Southern blot analysis. Overall regression analysis demonstrated yearly …             Aetiologies of Central Nervous System infections in adults in Kathmandu, Nepal: A prospective hospital-based study ▶     Abhishek Giri, Amit Arjyal, Samir Koirala et al.     We conducted a prospective hospital based study from February 2009-April 2011 to identify the possible pathogens of central nervous system (CNS) infections in adults admitted to a …             FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD ▶     Yusuke Fujioka, Shinsuke Ishigaki, Akio Masuda et al.     FUS is genetically and pathologically linked to amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD). To clarify the RNA metabolism cascade regulated …             The Directive 2010/63/EU on animal experimentation may skew the conclusions of pharmacological and behavioural studies ▶     Simone Macrì, Chiara Ceci, Luisa Altabella et al.     All laboratory animals shall be provided some form of environmental enrichment (EE) in the nearest future (Directive 2010/63/EU). Displacing standard housing with EE entails the …             Arginine insertion and loss of N-linked glycosylation site in HIV-1 envelope V3 region confer CXCR4-tropism ▶     Kiyoto Tsuchiya, Hirotaka Ode, Tsunefusa Hayashida et al.     The third variable region (V3) of HIV-1 envelope glycoprotein gp120 plays a key role in determination of viral coreceptor usage (tropism). However, which combinations of mutations …             Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing ▶     Wei Yan, Cory Smith, Linzhao Cheng     Our ability to precisely and efficiently edit mammalian and plant genomes has been significantly improved in recent years, partially due to increasing use of designer nucleases …             Cervical Cancer Screening Service Utilisation in UK ▶     Alexander Labeit, Frank Peinemann, Abbi Kedir     This study investigates empirically how past screening behaviour, individual and household characteristics affect the current uptake of cervical cancer screening in UK. For the …             A supramolecular approach to fabricate highly emissive smart materials ▶     Kai Liu, Yuxing Yao, Yuetong Kang et al.     The aromatic chromophores, for example, perylene diimides (PDIs) are well known for their desirable absorption and emission properties. However, their stacking nature hinders the …             Metabolic profiling of Alzheimer's disease brains ▶     Koichi Inoue, Haruhito Tsutsui, Hiroyasu Akatsu et al.     Alzheimer's disease (AD) is an irreversible, progressive brain disease and can be definitively diagnosed after death through an examination of senile plaques and neurofibrillary …             Intense THz pulses down-regulate genes associated with skin cancer and psoriasis: a new therapeutic avenue? ▶     Lyubov V. Titova, Ayesheshim K. Ayesheshim, Andrey Golubov et al.     Terahertz (THz) radiation lies between the infrared and microwave regions of the electromagnetic spectrum and is non-ionizing. We show that exposure of artificial human skin …                 • Careers & Jobs           naturejobs.com Science jobs of the week       Postdoctoral Fellow     University of Michigan - Ann Arbor            PhD studentship     Karlsruhe Institute of Kechnology (Campus North)            Postdoctoral Research Assistant     University of Oxford (Department of Pharmacology)            Project Manager     Imperial College London            8 PhD Fellowships     Cologne Cardiovascular Research Center/University Hospital of Cologne            Research Associate     UCL Institute of Neurology            Postdoctoral Fellow     University of Cincinnati            Cancer Research PhD Position     Medical University Vienna / SERD            Tenure Track Researcher     Tokai University            Postdoctoral Researcher     University of Pittsburgh          No matter what your career stage, student, postdoc or senior scientist, you will find articles on naturejobs.com to help guide you in your science career. 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