Nature Reviews Urology - Table of Contents alert Volume 10 Issue 8

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TABLE OF CONTENTS
August 2013 Volume 10 Number 8
Impact Factor 4.793*	In this issue Research Highlights News and Views Reviews Perspectives Also this month  Featured article: Image-guided robotic interventions for prostate cancer Ashwin N. Sridhar, Archie Hughes-Hallett, Erik K. Mayer, Philip J. Pratt, Philip J. Edwards, Guang-Zhong Yang, Ara W. Darzi & Justin A. Vale
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New Impact Factor We are pleased to announce that the new impact factor for Nature Reviews Urology is 4.793*. *2012 Journal Citation Reports® (Thomson Reuters, 2013)
RESEARCH HIGHLIGHTS Top Prostate cancer: Of mice and men—a co-clinical approach to CRPC Published online: 18 June 2013 p429 | doi:10.1038/nrurol.2013.141 PDF Infection: Formalin needle disinfection reduces sepsis risk of prostate biopsy Published online: 11 June 2013 p430 | doi:10.1038/nrurol.2013.132 PDF Incontinence: Novel 'split bladder' model to study micturition reflex in rats Published online: 18 June 2013 p430 | doi:10.1038/nrurol.2013.139 PDF Bladder cancer: Second-line nab-paclitaxel for advanced urothelial carcinoma Published online: 11 June 2013 p431 | doi:10.1038/nrurol.2013.131 PDF Prostate cancer: New class of drug that interferes with AR signalling Published online: 18 June 2013 p432 | doi:10.1038/nrurol.2013.138 PDF Incontinence: Intravesical 'shock absorber' provides relief from SUI Published online: 09 July 2013 p432 | doi:10.1038/nrurol.2013.150 PDF Prostate cancer: Aggressiveness—MRI can tell Published online: 18 June 2013 p433 | doi:10.1038/nrurol.2013.140 PDF Stones: Reducing radiation during PCNL Published online: 02 July 2013 p434 | doi:10.1038/nrurol.2013.147 PDF Incontinence: Novel grafting technique restores bladder function after spinal cord transection Published online: 16 July 2013 p434 | doi:10.1038/nrurol.2013.159 PDF IN BRIEF Kidney cancer: Time to recurrence ≤4 years after surgery predicts survival | Sexual dysfunction: Penile rehabilitation with sildenafil: nightly or on demand? | Prostate cancer: Reduced cancer-specific mortality with regular screening | Paediatrics: Videourodynamics less ionizing than VCUG PDF Urology JOBS of the week Post-doc fellow Baylor College of Medicine (BCM) Postdoctoral Associate Yale University, Department of Surgery, Section of Otolaryngology Bioinformatics Postdoctoral Fellow: Genomic Analysis of Circulating Tumor Cells Genome Institute of Singapore, A*STAR Senior postdoctoral scholar University Hospitals Case Medical Center and Case Western Reserve University Postdoctoral fellow University of California, Riverside More Science jobs from Urology EVENT Enhanced rare cell analysis – Visualize the invisible 30.10.13 Germany, Cologne More science events from
NEWS AND VIEWS		Top
Prostate cancer: Lymph node metastases: not always the same prognosis Riccardo Schiavina & Eugenio Brunocilla Published online: 11 June 2013 p435 | doi:10.1038/nrurol.2013.127 The presence of lymph node metastases is one of the most important prognostic factors after radical prostatectomy. However, not all patients with node-positive prostate cancer have the same risk of cancer-specific death and stratification can help identify those patients with few lymph node metastases who could expect a better prognosis. Full Text | PDF
Prostate cancer: The growing evidence supporting mid-life PSA testing Daniel Reinhardt & William J. Catalona Published online: 02 July 2013 p436 | doi:10.1038/nrurol.2013.144 Serum PSA testing remains controversial as the data regarding its utility are conflicting. However, a recent study adds to the growing body of evidence supporting its usefulness in middle-aged men, especially in the determination of the long-term risk of metastasis and death from prostate cancer. Full Text | PDF
Prostate cancer: Stratifying intermediate-risk patients for radiotherapy Mark K. Buyyounouski Published online: 25 June 2013 p438 | doi:10.1038/nrurol.2013.142 Radiotherapy is not a well-established option for men with intermediate-risk prostate cancer and further substratification of these patients could help to guide treatment decisions. Researchers have developed a new risk-classification system for intermediate-risk patients undergoing dose-escalated external-beam radiation therapy, but how effective is this system? Full Text | PDF
REVIEWS		Top
Cell mates: paracrine and stromal targets for prostate cancer therapy Pavel Sluka & Ian D. Davis Published online: 16 July 2013 p441 | doi:10.1038/nrurol.2013.146 A cancer in its entirety might be thought of as an organ comprising many parts. Thus, potential therapeutic targets for prostate cancer exist in the nonepithelial components of the tumour. In this Review, Sluka and Davis discuss the targets and pathways of the microenvironment that could be targeted for treatment of prostate cancer. Abstract | Full Text | PDF
Image-guided robotic interventions for prostate cancer Ashwin N. Sridhar, Archie Hughes-Hallett, Erik K. Mayer, Philip J. Pratt, Philip J. Edwards, Guang-Zhong Yang, Ara W. Darzi & Justin A. Vale Published online: 18 June 2013 p452 | doi:10.1038/nrurol.2013.129 Here, Sridhar and co-authors describe the applications of robotic technology in combination with image guidance in the surgical, including organ preserving, management of prostate cancer. Although several of these platforms have been developed in the diagnostic setting, their use in surgical and nonexcisional interventions is increasing. Abstract | Full Text | PDF
Fertility preservation strategies for male patients with cancer Darren J. Katz, Thomas F. Kolon, Darren R. Feldman & John P. Mulhall Published online: 09 July 2013 p463 | doi:10.1038/nrurol.2013.145 Fertility preservation is an essential consideration of cancer management. Katz et al. outline the issues related to infertility for both prepubertal and postpubertal male patients with cancer and review the currently available approaches of fertility preservation. Experimental strategies that are under investigation for fertility preservation both before and after cancer treatment are also discussed. Abstract | Full Text | PDF
Defining the threshold for significant versus insignificant prostate cancer Theo H. Van der Kwast & Monique J. Roobol Published online: 28 May 2013 p473 | doi:10.1038/nrurol.2013.112 In this Review, Van der Kwast and Roobol consider the risk of overdiagnosis of PSA-detected prostate cancers and reassess the pathological definition of insignificant prostate cancer based on an extensive literature review. Abstract | Full Text | PDF
PERSPECTIVES		Top
OPINION Ex vivo culture of human prostate tissue and drug development Margaret M. Centenera, Ganesh V. Raj, Karen E. Knudsen, Wayne D. Tilley & Lisa M. Butler Published online: 11 June 2013 p483 | doi:10.1038/nrurol.2013.126 In this Perspectives article, Centenera et al. chronicle the development of ex vivo culture models that utilize tumour material from men with prostate cancer and discuss the advantages, limitations, and potential applications of these systems to expedite the evaluation of novel drugs for the treatment of prostate cancer. Abstract | Full Text | PDF
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*Journal Citation Reports, Thomson, 2012. Nature Reviews Urology was previously published as Nature Clinical Practice Urology.

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