Tuesday, 23 July 2013

CDC HIV/Hepatitis/STD/TB Prevention News Update 07/23/2013

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HIV/Hepatitis/STD/TB News - CDC Prevention News Update
CDCNPIN Prevention Newsletter 7/23/2013
National News

Drug to Treat HIV/AIDS Side Effect Mired in Lawsuit

International News

East Asian Students Less Sexually Active but Sexually Risky, UBC Study Shows

Medical News

Mold Toxins Tied to AIDS Epidemic

Local and Community News

At Least 1,400 Students, Staff at Lee High Should Get TB Tests, Health Officials Say

Fil-Ams at High Risk of Hepatitis-B: Free Testing in SF Bay Area

News Briefs

Sixth Annual World Hepatitis Day Takes Place on July 28

Health Information Authority: STD Cases in Slovakia

OraSure Founders Reunite for New Project

National News
National News Drug to Treat HIV/AIDS Side Effect Mired in Lawsuit

UNITED STATES :: HIV/AIDS
New York Amsterdam News (07.18.2013) :: By Glenn Townes

Napo Pharmaceuticals has filed a lawsuit against Salix Pharmaceuticals that has delayed availability of the drug Fulyzaq, which the two firms partnered in 2008 to develop. The US Food and Drug Administration (FDA) approved Fulyzaq in 2012 for the prevention of “excessive” diarrhea, a common side effect of HIV antiretroviral therapy (ART).

Salix announced in May that the company was working with FDA to expedite Fulyzaq distribution, and stated in June that the drug was available from Walgreens Specialty Pharmacies. However, many doctors treating HIV-infected people reported that their patients were unable to obtain Fulyzaq at Walgreens or any other pharmacy, according to Napo’s legal representative.

Until the legal issues are settled, patients with excessive gastrointestinal adverse reactions to ART will continue to suffer. One such individual is a Washington, DC, resident who reported that he has lived with HIV since the 1980s. He noted that ART successfully reduced his viral load to virtually undetectable levels, but he still had “severe intestinal and bowel issues” because of his drug regimen.
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International News
International News East Asian Students Less Sexually Active but Sexually Risky, UBC Study Shows

VANCOUVER, CANADA :: HIV/AIDS,STDs
Vancouver Sun (07.17.2013) :: By Zoe McKnight

A new study by the University of British Columbia (BC) School of Nursing found that language barriers might be putting the sexual health of some new Canadians at risk. According to Yuko Homma, a post-doctoral fellow and the study’s lead author, East Asian high school students in this province were less likely to be sexually active, but those who were active engaged in riskier sexual behavior. Study authors suggested that language and cultural barriers might be preventing parents from speaking frankly with their children about sex.

“In BC, there is a growing population of East Asians, particularly Chinese and Koreans. East Asian student health impacts general Canadian health,” said Homma. She would like to see more culturally appropriate sex education taught in both English and the students’ first language. The province’s Ministry of Education mandates sex education as part of its health and career education curriculum.

While research indicated that sexual activity had become more common among North American adolescents, only 10 percent of East Asian adolescents in BC reported having sexual intercourse. However, seven out of 10 sexually active East Asian youth reported high-risk behavior, according to the study. The report used 2008 data from the provincial Adolescent Health Survey and responses from nearly 30,000 students in grades 7–10 from China, Korea, and Japan. The majority of these students are first-generation immigrants. More than half of respondents spoke their native language at home, which researchers noted might indicate closer ties to more traditionally conservative cultures. “I hate to make generalizations,” said Kristen Gilbert, a senior educator at Options for Sexual Health agency, “but it’s common for me to have Asian students in the class who are surprised by the information, even basic reproductive biology.”

According to Saleema Noon, an independent Vancouver-based sex educator, “I think it comes down to religion and culture ... Most of us didn’t learn much from our own parents, and we live in a culture that’s so much more sexually open than Asia.” She continued that, in an “ideal world,” schools would translate educational material into several languages and send it home to parents as well. Sex remained a taboo topic for many families, but Noon noted that attitudes were slowly changing.

The full study, “Sexual Health and Risk Behavior Among East Asian Adolescents in British Columbia,” was published online in the Canadian Journal of Human Sexuality (2013; doi:10.3138/cjhs.927).
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Medical News
Medical News Mold Toxins Tied to AIDS Epidemic

GHANA; UNITED STATES :: HIV/AIDS
New York Times (07.22.2013) :: By Donald G. McNeil Jr.

A new study from researchers at the University of Alabama at Birmingham and colleagues has examined the impact of aflatoxins on the AIDS epidemic in Africa. Aflatoxins are poisons produced by aspergillus fungi that can be found on damp grains, nuts, and beans, usually in hot humid climates. Federal law limits the allowable amount of these highly dangerous toxins in food to 20 parts per billion. High doses of aflatoxins can be deadly; exposure even to low doses could cause liver cancer. Aflatoxins also have been found to be immunosuppressive, possibly causing increased immunosuppression in HIV-positive individuals.

Because African countries rely heavily on several crops that develop aspergillus, researchers investigated the association between aflatoxins and HIV. They measured the blood levels of aflatoxins and the disease in 314 HIV-positive Ghanaians who had never been on antiretroviral therapy. Results showed that higher aflotoxin levels in participants’ blood often coincided with higher HIV blood levels, even for individuals with high levels of CD4 blood cells. These participants with high CD4 blood cells had not been infected long and were not eligible to begin antiretroviral therapy, under World Health Organization guidelines. Researchers believed that aflatoxins either produced proteins that contributed to HIV reproduction or reduced the number of white blood cells in some way, making the virus’s attack on the immune system more powerful.

The full report, “Association Between High Aflatoxin B1 Levels and High Viral Load in HIV-Positive People,” was published online in the World Mycotoxin Journal (2013; doi 10.3920/WMJ2013.1585).
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Local and Community News
Local and Community News At Least 1,400 Students, Staff at Lee High Should Get TB Tests, Health Officials Say

VIRGINIA :: TB
Washington Post (07.22.2013) :: By T. Reese Shapiro

Fairfax County, Va., public health officials will offer free TB screening beginning August 3 to all 1,400 faculty, staff, and students of Lee High School, in response to public concern regarding recently diagnosed TB cases. Last spring, three Lee High students tested positive for active TB. In June, the Fairfax County Health Department asked 400 students and 30 staff members who had been in close contact with the TB-infected students to undergo TB testing. Approximately one week later, the health department expanded testing to 60 additional possible contacts from other Fairfax County schools. The screening identified an undisclosed number of additional latent TB cases—a noncontagious form of the bacterial infection—that could progress to active TB if left untreated. The department has tested close to 300 people since the outbreak.

Typically, approximately 1 percent of US-born residents would test positive for latent TB; approximately 5 percent of the recently tested US-born Lee High group received a positive test result, according to Fairfax County Health Director Gloria Addo-Ayensu. Spokesperson Glen Barbour stated that incidence among the foreign-born Lee High group tested for TB was comparable to the worldwide TB rate, which ranged from 5 to 33 percent. Jane Moore, director of TB control and prevention for the Virginia Department of Health, reported that Virginia health departments investigate 5–10 TB cases in schools annually. One-third of Virginia’s TB cases in 2012 occurred in Fairfax County. Northern Virginia, home to a diverse immigrant population and many US residents who work internationally, accounted for more than half of all Virginia TB cases.

The Fairfax County Health Department scheduled the August 3 testing for all Lee High students, staff, and faculty to alleviate community concern and to identify all TB cases before school reconvened on September 3.

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  Fil-Ams at High Risk of Hepatitis-B: Free Testing in SF Bay Area

CALIFORNIA :: Viral Hepatitis
Inquirer Global Nation (The Philippines) (07.22.2013) :: By Rose Paquette

San Francisco’s Hep B Free Campaign recently launched a Free Hep B test clinic at North East Medical Services (NEMS) in Daly City. The San Francisco campaign started in coordination with the city’s public health clinic, the Asian Week Foundation, and the City of San Jose. Genevieve V. Jopanda, Hep B Free’s executive director, stated that among Asians, Filipinos had the third highest hepatitis B virus (HBV) infection rates, after Chinese and Vietnamese residents. Jopanda explained that two out of three HBV-infected Asians/Pacific Islanders did not know they were infected, and one in four of these patients would develop liver cancer or liver disease if they did not receive treatment. She noted that chronic HBV infection was associated with approximately 80 percent of all liver cancers. The NEMS clinic is giving free HBV screening every Thursday between 2:00 p.m. and 4:00 p.m. No appointment is necessary. The clinic will also provide vaccinations at discounted rates to low-income patients.

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News Briefs
News Briefs Sixth Annual World Hepatitis Day Takes Place on July 28

MASSACHUSETTS :: Viral Hepatitis
The Rainbow Times (07.22.2013)

In collaboration with the World Health Organization, the World Hepatitis Alliance will sponsor the sixth annual World Hepatitis Day on July 28. Additionally, AIDS Action Committee of Massachusetts will offer confidential hepatitis information, referrals, and support Monday through Thursday from 9:00 a.m. to 8:00 p.m. and Friday 9:00 a.m. to 5:00 p.m. For further information, call (800) 235–2331 or e-mail hotline@aac.org. An estimated 110,000 individuals with viral hepatitis currently live in Massachusetts, with another 7,000–10,000 new cases diagnosed annually.
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  Health Information Authority: STD Cases in Slovakia

SLOVAKIA :: HIV/AIDS,STDs
The Slovak Spectator (07.18.2013)

According to a July 16 statement from National Centre for Health Information Spokesperson Peter Bubla, STD cases in Slovakia rose by 105, to a total of 1,142 recorded cases for 2012. Syphilis cases dropped slightly to 302, but 176 cases of gonorrhea represented a rise of 21 cases for the year. Slovakia reported 663 cases in 2012 of “other STDs” such as chlamydia, genital herpes, and HIV/AIDS, which represented a growth of 99 cases from the previous year. Bubla said that younger age groups reported a higher case incidence, with 213 cases among youths ages 15–24 and 238 cases among those 25–34 years of age.

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  OraSure Founders Reunite for New Project

PENNSYLVANIA :: HIV/AIDS,TB
Morning Call (Allentown, PA) (07.18.2013) :: By Sam Kennedy

Two founders of Bethlehem, Pa.-based OraSure Technologies, maker of the OraQuick HIV test, will work together to create a TB test. In 1988, Sam Niedbala and Mike Gausling partnered with two other friends to form what would become OraSure. Niedbala's new company, TB Biosciences, recently announced it received $1.5 million from a group of investors led by Originate Ventures, the venture capital fund co-founded by Gausling. TB Biosciences is working on a means of diagnosing the disease using antibodies found in the blood of patients with active TB. Niedbala believes that developing an improved TB test is part of the larger fight against HIV because so many HIV-positive individuals actually died of TB. According to TB Biosciences, preliminary trials indicated a 90-percent accuracy rate for the company’s technology, which the New York University (NYU) School of Medicine has developed throughout the past two decades. "This would be a major breakthrough in tuberculosis testing and could go a long way to saving many lives each year," said Frank Rimalovski, executive director of the NYU Innovation Venture Fund.
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The CDC National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention provides the above information as a public service only. Providing synopses of key scientific articles and lay media reports on HIV/AIDS, viral hepatitis, other sexually transmitted diseases, and tuberculosis does not constitute CDC endorsement. The above summaries were prepared without conducting any additional research or investigation into the facts and statements made in the articles being summarized, and therefore readers are expressly cautioned against relying on the validity or invalidity of any statements made in these summaries. This daily update also includes information from CDC and other government agencies, such as background on Morbidity and Mortality Weekly Report (MMWR) articles, fact sheets, and announcements. Reproduction of this text is encouraged; however, copies may not be sold, and the CDC HIV/Hepatitis/STD/TB Prevention News Update should be cited as the source of the information. Contact the sources of the articles abstracted above for full texts of the articles.

The Prevention News Update electronic mailing list is maintained by the National Prevention Information Network (NPIN), part of the Centers for Disease Control and Prevention's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention. Regular postings include the Prevention News Update, select articles from the Morbidity and Mortality Weekly Report series, and announcements about new NPIN products and services.

 

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